ChemInform Abstract: Taxezopidines J, K, and L, New Taxoids from Taxus cuspidata Inhibiting Ca2+-Induced Depolymerization of Microtubules.

✍ Scribed by Hideyuki Shigemori; Cecilia A. Sakurai; Hirokazu Hosoyama; Akio Kobayashi; Shinichiro Kajiyama; Jun'ichi Kobayashi

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199927197

✦ Synopsis

Taxezopidines J (I), K (II), and L (III) are isolated from the seeds of title species. Their structures are determined by spectroscopic and chemical means. Taxezopidines K and L markedly inhibit Ca 2+ -induced depolymerization of microtubules.

-(SHIGEMORI, HIDEYUKI; SAKURAI, CECILIA A.;