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ChemInform Abstract: Tandem SN2-Michael Addition to Vinylogous Carbonates for the Stereoselective Construction of 2,3,3,5-Tetrasubstituted Tetrahydrofurans.

✍ Scribed by Santosh J. Gharpure; S. Raja Bhushan Reddy

Publisher
John Wiley and Sons
Year
2011
Weight
37 KB
Volume
42
Category
Article
ISSN
0931-7597

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✍ E. P. SCHREINER; A. PRUCKNER πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 1 views

Syn-Selective Michael Addition of Amines to Bis-enones: Synthesis of 1, 3,4,7-Tetrasubstituted (4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-2H-1,3-diazepin-2-ones. -The O-protected title compounds (IX), seven-membered cyclic ureas, are useful as intermediates in the synthesis of HIV-proteinase inhibitors.