✦ LIBER ✦
ChemInform Abstract: Synthetic Study on Naturally Occurring Acetylenic Spiroacetal Enol Ethers: The First Access to Optically Active 3,4-Diacetoxy-2-formylmethylene-1,6-dioxaspiro[4,5]decanes.
✍ Scribed by Hiroaki Toshima; Hisateru Aramaki; Akitami Ichihara
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
✦ Synopsis
Synthetic Study on Naturally Occurring Acetylenic Spiroacetal Enol Ethers: The First Access to Optically Active 3,4-Diacetoxy-2formylmethylene -1,6-dioxaspiro[4,5]decanes. -In view of the interest in the synthesis of naturally occuring acetylenic spiroacetal enol ethers, the title spirodecanes are prepared by intramolecular addition of keto-alcohol (V). The stereogenic centers are introduced via Sharpless asymmetric dihydroxylation of conjugated ketone (III) with a modified AD-mix-α. -(TOSHIMA, HIROAKI;