ChemInform Abstract: Synthetic and Photochemical Studies of N-Arenesulfonyl Amino Acids.

✍ Scribed by George Papageorgiou; John E. T. Corrie

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 33 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199924089

✦ Synopsis

Synthetic and Photochemical Studies of N-Arenesulfonyl Amino Acids.

-Irradiation of the title compounds (V), (VII), (X), and (XI) results in cleavage of the sulfonamide with very sub-stoichiometric release of the intact amino acid because of concurrent decarboxylation during photoreaction. Best release (30%) of free amino acid is observed for compound (VIIa) having an ortho carboxylate group. This indicates that such molecules are not effective for photorelease of neuroactive amino acids. -(PAPAGEORGIOU, GEORGE;