ChemInform Abstract: Synthetic and Mechanistic Studies of the Aza-Retro-Claisen Rearrangement. A Facile Route to Medium Ring Nitrogen Heterocycles.

✍ Scribed by Robert K. Jr. Boeckman; Nathan E. Genung; Ke Chen; Todd R. Ryder

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 60 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201034186

✦ Synopsis

Abstract

Heating of oxepines and oxacenes of type (I) and (IV) as well as cyclobutanecarboxaldehydes like (VII) with Staudinger reagents is found to provide an efficient approach to medium ring nitrogen heterocycles.