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ChemInform Abstract: Synthesis of β-Lactones. Part 9. Synthesis of Enantiomerically Pure β-Lactones by the Tandem Aldol—Lactonization. A Highly Efficient Access to (3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one (IV), the Key Intermediate for the Enzyme Inhibitors Tetrahydrolipstatin (VIa) and Tetrahydroesterastin (VIb).
✍ Scribed by Christine Wedler; Burckhard Costisella; Hans Schick
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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