ChemInform Abstract: Synthesis of α-Heterosubstituted Glycine Derivatives from Dihaloethanamides.
✍ Scribed by P. D. BAILEY; S. R. BAKER; A. N. BOA; J. CLAYSON; G. M. ROSAIR
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
The diastereoselective synthesis of α-amino esters from the glycine ester (I) employing the sulfonamides (II) as chiral auxiliaries works well for α-alkylation with methyl iodide. Ethylation, allylation, and benzylation proceeds with fair stereoselectivity, but pure diastereomers can be obtained by
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