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ChemInform Abstract: Synthesis of Valsartan via Decarboxylative Biaryl Coupling.

โœ Scribed by Lukas J. Goossen; Bettina Melzer

Publisher
John Wiley and Sons
Year
2008
Weight
38 KB
Volume
39
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โ€œFull Textโ€ option. The original article is trackable via the โ€œReferencesโ€ option.

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Synthesis of Biaryls and Aryl Ketones vi
Synthesis of Biaryls and Aryl Ketones via Microwave-Assisted Decarboxylative Cross-Couplings
โœ Lukasโ€…J. GooรŸen; Bettina Zimmermann; Christophe Linder; Nuria Rodrรญguez; Paulโ€…P. ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 216 KB ๐Ÿ‘ 2 views

## Abstract A protocol for the microwaveโ€assisted decarboxylative crossโ€couplings of carboxylic acid salts with aryl halides has been developed that allows the synthesis of various biaryls and aryl ketones in high yields. After careful adaptation of the bimetallic catalyst system and reaction condi