ChemInform Abstract: Synthesis of Triazole-Linked Amino Acid-Aryl C-Glycoside Hybrids via Click Chemistry as Novel PTP1B Inhibitors.

✍ Scribed by Jia Wang; Xiaopeng He; Lixin Gao; Li Sheng; Xiaoxin Shi; Jia Li; Guorong Chen

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 28 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201146185

✦ Synopsis

Abstract

Triazolyl phenylalanine and tyrosine‐aryl C‐glycoside hybrids are readily synthesized in high yield via microwave‐assisted Cu(I)‐catalyzed azide‐alkyne 1,3‐dipolar cycloaddition.