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ChemInform Abstract: Synthesis of Tetrahydroisoquinoline Antitumor Natural Products: Construction of Tricyclic Lactams Through Pictet—Spengler-Type Cyclization of N-Methyl-3-arylmethylpiperazine-2,5-dione with Ethyl Diethoxyacetate.

✍ Scribed by Masashi Yokoya; Osamu Kawachi; Naoki Saito

Publisher: John Wiley and Sons
Year: 2009
Weight: 27 KB
Volume: 40
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200918159

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ChemInform Abstract: Synthesis of Renier

ChemInform Abstract: Synthesis of Renieramycins: Construction of the Core Ring System of Cribrostatin 4 Through Modified Pictet—Spengler Cyclization of 3,6-Bisarylpiperazine-2,5-dione with Diethoxyethyl Benzoate.

✍ Masashi Yokoya; Hiroshi Ito; Naoki Saito 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

## Abstract The synthesis of the compound (V), which is a key intermediate in the synthesis of cribrostatin 4 can be achieved by a stereoselective cyclization, cf.