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ChemInform Abstract: Synthesis of Some New Pyrazolo[3,4-d]pyrimidine Derivatives of Expected Anticancer and Radioprotective Activity.

✍ Scribed by Mostafa M. Ghorab; Fatma A. Ragab; Saleh I. Alqasoumi; Ahmed M. Alafeefy; Sarah A. Aboulmagd

Publisher
John Wiley and Sons
Year
2010
Weight
117 KB
Volume
41
Category
Article
ISSN
0931-7597

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## Abstract 2‐Benzyl‐ and 2‐aryloxymethyl‐3‐amino‐1‐phenyl‐pyrazolo[3,4‐__d__]pyrimidine‐4‐ones **__5a–f__** have been synthesized by reacting the corresponding arylacetylamino derivatives **__3a–f__** with hydrazine hydrate. Thionation of compounds **__5d–f__** by action of P~2~S~5~ in pyridine yi