Synthesis of reagents for the one step i
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William L Scott; Cynthia Cwi
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Article
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1996
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Elsevier Science
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English
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Two new reagents, 1 and 2, were prepared for the one step incorporation of hydrazide functionality onto the lysine residues of proteins. Their utility as linking reagents was demonstrated by their use in the coupling of two model aldehydes, and the anticancer agent doxorubicin, to a monoclonal antib