ChemInform Abstract: Synthesis of Pyridine Alkaloids via Pd-Catalyzed Coupling of 3-Iodopyridine, 1,ω-Dienes and Nitrogen Nucleophiles.
✍ Scribed by Richard C. Larock; Yao Wang
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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Efficient Synthesis of 1,1-Diaryl 1,2-Dienes via Pd(0)-Catalyzed Coupling of Aryl Halides with Allenic/Propargylic Zinc Reagents. -The title reaction is proposed to involve oxidative addition of halides to Pd(0) to form an organopalladium intermediate. This is trapped by an allenic or propargylic z