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ChemInform Abstract: Synthesis of Polyhydroxylated Piperidine Alkaloids via Reactions of Chelated Amino Acid Ester Enolates

โœ Scribed by Uli Kazmaier


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
30
Category
Article
ISSN
0931-7597

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A Short Synthesis of Polyhydroxylated Pi
โœ Uli Kazmaier; Roland Grandel ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 432 KB ๐Ÿ‘ 2 views

Aldol reactions of a chelated glycine ester enolate with a azasugars by cyclization using the Mitsunobu reaction. An interesting epimerization was observed during the chiral aldehyde gives rise to the corresponding polyhydroxylated amino acid with excellent induced cyclization. The potential glycosi