ChemInform Abstract: Synthesis of Optically Pure 2-Azetidinones Having N-Dehydroamino Acid Side-Chains.
β Scribed by B. ALCAIDE; C. POLANCO; M. A. SIERRA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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An efficient, three-step synthesis of N-vinyl-2-azetidinones 7 selenylation, and finally m-CPBA treatment, afforded Nvinyl-2-azetidinones 7 in fair to excellent yields, with starting from Ξ±or Ξ²-amino ester imines 4 has been developed. Staudinger reaction between imines 4 and a retention at the remai
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