ChemInform Abstract: Synthesis of Optically Active Hydroxyalkylbenzothiazepinones by Ring Transformation of 2-Alkylidenelactones with o-Aminothiophenol.
β Scribed by Andreas Otto; Juergen Liebscher
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 29 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Synthesis of Chiral 4-(Ο-Hydroxyalkyl)pyrazolidin-3-ones by Ring-Chain Transformation of Ξ±-Alkylidenelactones with Hydrazines. -This is the first access to optically active 4-(Ο-hydroxyalkyl)pyrazolidin-3-ones. The lactone (IX), however, cannot be transformed into the corresponding pyrazolidinone.