ChemInform Abstract: Synthesis of Novel Vitamin D Analogs
β Scribed by R. M. MORIARTY; R. PENMASTA; M. S. RAO; L. GUO; F. WERNER; R. G. MEHTA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 24 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
A series of analogs of 1,25-dihydroxycholecalciferol was obtained with an additional chiral center at the terminus of the aliphatic side chain (C-25). The analogs were obtained from (+)-(R)-and (-)-(S)-2-methylglycidols, by opening of the oxirane ring with the carbanions derived from vitamin D C 23a
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