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ChemInform Abstract: Synthesis of Novel Spiro(indolone-3,2′-[1,3,4]thiadiazol)-2-ones and Evaluation of Their Antidepressant and Anticonvulsant Activities.

✍ Scribed by Alaa A. Hassan; Fathy F. Abdel-Latif; Ahmed M. Nour El-Din; Mohamed Abdel-Aziz; Sara M. Mostafa; Stefan Braese

Publisher
John Wiley and Sons
Year
2012
Weight
23 KB
Volume
43
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

The compounds (III) exhibit remarkable antidepressant activity compared with imipramine and compared with phenobarbital they show a good protection against clonic seizures induced by ip injection of pentylenetetrazol in mice (no yields given).

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