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ChemInform Abstract: Synthesis of Novel N1-(2-Furanidyl)-5-fluorouracil Derivatives of α-Hydroxy(thio)phosphonates

✍ Scribed by Guochen Chi; Xiaodong Wang; Ruyu Chen

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
33
Category
Article
ISSN
0931-7597

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Synthesis of novel N1-(2-furanidyl)-5-fl
Synthesis of novel N1-(2-furanidyl)-5-fluorouracil derivatives of α-hydroxy(thio)phosphonates
✍ Guochen Chi; Xiaodong Wang; Ruyu Chen 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB

## Abstract Several __N__^1^‐(2‐furanidyl)‐5‐fluorouracil derivatives of α‐hydroxythiophosphonates were synthesized via oxidation by Moffatt's method of __N__^1^‐(2‐furanidyl)‐__N__^3^‐(hydroxyalkyl)‐5‐fluorouracil, followed by the addition of diethyl thiophosphite. The phosphonate products were ob