ChemInform Abstract: Synthesis of Nonracemic Dimethyl α-(Hydroxyfarnesyl)phosphonates via Oxidation of Dimethyl Farnesylphosphonate with (Camphorsulfonyl)oxaziridines.

ChemInform Abstract: Enantioselective Sy

ChemInform Abstract: Enantioselective Synthesis of α-Hydroxy Phosphonates via Oxidation with (Camphorsulfonyl)oxaziridines.

✍ D. M. POGATCHNIK; D. F. WIEMER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Enantioselective Synthesis of α-Hydroxy Phosphonates via Oxidation with (Camphorsulfonyl)oxaziridines. -Chiral dichloro oxaziridines (OXA) are used for the enantioselective introduction of the hydroxy group to prochiral phosphonates. The (+)-reagent favors the formation of (S)-products. Phosphonate