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ChemInform Abstract: Synthesis of New Pyrrolo(3,4-b)- and (3,4-c)pyridin(on)es and Related 1,7-Naphthyridinones and 2,7-Naphthyridines via Intramolecular Diels- Alder Reactions of 2(1H)-Pyrazinones.

โœ Scribed by K. J. BUYSENS; D. M. VANDENBERGHE; G. J. HOORNAERT


Book ID
112039859
Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
27
Category
Article
ISSN
0931-7597

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Novel intramolecular diels-alder reactio
โœ Edward C. Taylor; John E. Macor ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 191 KB

Alkylation of 1,2,4-triazine-6-thiones with 4-iodobutyne, followed by oxidation to the sulfoxide and intramolecular cycloaddition (at room temperature), gives 2,3-dihydrothieno[2,3-c]pyridines, which are readily dehydrated with acetic anhydride to thieno[2,3\_c]pyridines. The same series of reactio