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ChemInform Abstract: Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Antiinflammatory Evaluation.

✍ Scribed by Osama I. El-Sabbah; Samy M. Ibrahim; Mohamed M. Baraka; Hend Kothayer

Publisher
John Wiley and Sons
Year
2010
Weight
83 KB
Volume
41
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

New 2,3‐dihydroquinazolin‐4(1H)‐ones combined with either chalcone (III), pyrazole (IV), or thiazole (VIII) moieties are synthesized and evaluated for their analgesic and antiinflammatory activity.

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ChemInform Abstract: Synthesis of 2,3-Di
ChemInform Abstract: Synthesis of 2,3-Dihydroquinazoline-4(1H)-ones.
✍ Hamid Reza Shaterian; Ali Reza Oveisi; Moones Honarmand πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 39 KB

## Abstract A practical method for the synthesis of the title compounds via three‐component reaction of isatoic anhydride (I) with aromatic aldehydes and primary amines or ammonium salts under solvent‐free conditions is developed.