## Abstract via three‐component condensation of aminoquinoline (I) with cyclohexanedione (III) and various aldehydes
ChemInform Abstract: Synthesis of Methyl 12-Aryl-9,9-dimethyl-11-oxo-7,8,9,10,11,12-hexahydrobenzo [a]acridine-10-carboxylate.
✍ Scribed by N. G. Kozlov; S. L. Bondarev; A. P. Kadutskii; L. I. Basalaeva
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 44 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
The title compounds are obtained in a three‐component condensation of 2‐naphthylamine, aromatic aldehydes, and 2,2‐dimethyl‐4,6‐dioxocyclohexanecarboxylate.
📜 SIMILAR VOLUMES
## Abstract A Hofmann—Martius rearrangement mechanism is suggested for the reaction of known azomethines (I) with cyclohexane‐1,3‐dione.
## Abstract magnified image A series of sixteen new derivatives have been obtained and all have potentially useful pharmacological activity. The treatment of 7‐[(__o__‐chloro and __p__‐bromo)phenyl]‐7,8,9,10,11,12‐hexahydrobenz[__c__]acridin‐8‐one and Lawesson's reagent obtains the corresponding 7