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ChemInform Abstract: Synthesis of Linearly Fused Tetracyclic Heterocycles Through a Novel Base-Catalyzed Intramolecular Rearrangement Involving Scission of N—N Bond.

✍ Scribed by B. Prabhuswamy; Sarvottam Y. Ambekar


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Synthesis of Linearly Fused Tetracyclic Heterocycles Through a Novel Base-Catalyzed Intramolecular Rearrangement Involving Scission of N-N Bond.

-Acid-mediated condensation of 2-chloro-3-formylquinolines (I) with triazoles (II) provides the s-triazolothiadiazepinoquinolines (III) (6 examples), which smoothly undergo a novel base-catalyzed intramolecular rearrangement to the s-triazolothiazinoquinolines (IV) involving scission of an N-N bond. -(