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ChemInform Abstract: Synthesis of Lacto-N-neohexaose and Lacto-N-neooctaose Using the Dimethylmaleoyl Moiety as an Amino Protective Group.

โœ Scribed by Mohamed R. E. Aly; El-Sayed I. Ibrahim; El-Sayed H. E. El-Ashry; Richard R. Schmidt


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
31
Category
Article
ISSN
0931-7597

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Synthesis of Lacto-N-neohexaose and Lact
โœ Mohamed R. E. Aly; El-Sayed I. Ibrahim; El-Sayed H. E. El-Ashry; Richard R. Schm ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 410 KB ๐Ÿ‘ 2 views

The N-DMM-Protected lactosamine derivative 2 was readily neohexaose). Glycosylation of acceptor 10 with donor 4 furnished tetrasaccharide 16 which, employing standard transformed into the corresponding glycosyl donor 4 and into acceptor 5. A TMSOTf-catalyzed glycosidation afforded the procedures, ga