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ChemInform Abstract: Synthesis of Highly Enantioenriched C-Tertiary Amines from Boronic Esters: Application to the Synthesis of Igmesine.

โœ Scribed by Viktor Bagutski; Tim G. Elford; Varinder K. Aggarwal


Publisher
John Wiley and Sons
Year
2011
Weight
102 KB
Volume
42
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Highly Enantiosel
โœ Hon-Wah Man; William C. Hiscox; Donald S. Matteson ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 1 views

A Highly Enantioselective and Diastereoselective Synthesis of Cyclobutanes via Boronic Esters. -Deprotection of enantiopure boronate (II) with LDA provides a spirocyclic boronate which rearranges in high enantiopurity to the cyclobutanone (IV) on treatment with catalytic MgBr 2 . Interestingly, no c