ChemInform Abstract: Synthesis of gem-Difluoromethylenated Analogues of Anamarine.

✍ Scribed by Jing Lin; Xiao-Long Qiu; Feng-Ling Qing

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 46 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201042192

✦ Synopsis

Abstract

A novel difluorinated anamarine derivative (IX) is prepared via indium mediated difluoropropargylation of aldehyde, obtained by oxidation of alcohol (II), and TEMPO‐catalyzed oxidative cyclization of diol (VI) as key steps.