𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Synthesis of Esters from Silyl Ethers and Acyl Chlorides: Catalysis by Quaternary Ammonium Chlorides.

✍ Scribed by S. BRANDAENGE; H. LEIJONMARCK; T. MINASSIE

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
28
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Synthesis of Esters from Silyl Ethers and Acyl Chlorides: Catalysis by Quaternary Ammonium Chlorides. -Quaternary ammonium chlorides are more efficient than other ammonium halides as catalysts in the title reaction. Acetyl chloride reacts faster than benzoyl chloride and trimethylsilyl ethers react faster than silyl ethers with bulkier Si-substituents, e.g. (I). The regioselectivity in monoacylation of (I) increases continuously from 96.6% after 1 h to 99.3% after 7 h, but during the second acylation to give (V) there is some decrease in isomeric purity (from 99.3 to 98.2%) that can be raised to 98.9% with tin(IV) chloride as catalyst instead of Bu4NCl.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: A Novel Synthesis o
ChemInform Abstract: A Novel Synthesis of Chiral Tetrahydroisoquinolines Employing Silyl Enol Ethers in the Presence of Chiral Acyl Chlorides.
✍ Takashi Itoh; Kazuhiro Nagata; Michiko Miyazaki; Akio Ohsawa πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 29 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v