Benzyl aziridine-2-carboxylates have been obtained in high yield and selectivity by conjugate addition of ammonia to ct,13-unsaturated chiral imides followed by treatment with lithium benzyloxide. A ring-expansion of the aziridine to an oxazoline allowed the determination of the absolute stereochemi
ChemInform Abstract: Synthesis of Enantiomerically Pure trans-Aziridine-2-carboxylates by Diastereoselective Gabriel-Cromwell Reaction.
β Scribed by G. CARDILLO; L. GENTILUCCI; C. TOMASINI; M. P. V. CASTEJON-BORDAS
- Book ID
- 112034576
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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