ChemInform Abstract: Practical Synthesis
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N. K. YEE; L. J. NUMMY; D. P. BYRNE; L. L. SMITH; G. P. ROTH
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Article
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2010
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John Wiley and Sons
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Practical Synthesis of an Enantiomerically Pure trans-4,5-Disubstituted 2-Pyrrolidinone via Enzymatic Resolution. Preparation of the LTB 4 Inhibitor BIRZ-227. -The efficient synthesis of rac. (II) in a simple one-pot procedure was already described. A novel enzymatic resolution of its rac derivative