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ChemInform Abstract: Synthesis of Diphosphite Ligands Derived from Glucopyranoside and Their Application in the Cu-Catalyzed Asymmetric 1,4-Addition of Organozinc to Enones.

✍ Scribed by Qing-Lu Zhao; Man Kin Tse; Lai-Lai Wang; Ai-Ping Xing; Xianxing Jiang


Publisher
John Wiley and Sons
Year
2011
Weight
37 KB
Volume
42
Category
Article
ISSN
0931-7597

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Synthesis of New Chiral Aryl Diphosphite
✍ Lailai Wang; Yue-Ming Li; Chiu-wing Yip; Liqin Qiu; Zhongyuan Zhou; Albertβ€…S.β€…C. πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 146 KB πŸ‘ 2 views

## Abstract New chiral aryl diphosphite ligands based on the pyranoside backbones of glucose and galactose were prepared. These ligands were tested in the Cu‐catalyzed asymmetric conjugate addition of diethylzinc to cyclic enones with up to 88% ee. The stereoselectivity was found to be dependent on