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ChemInform Abstract: Synthesis of Conformationally Constrained Adamantane Imidazolines with Trypanocidal Activity.

✍ Scribed by Ioannis Papanastasiou; Andrew Tsotinis; George B. Foscolos; S. Radhika Prathalingam; John M. Kelly

Book ID: 102026561
Publisher: John Wiley and Sons
Year: 2009
Weight: 37 KB
Volume: 40
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200905117

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Synthesis of conformationally constraine

Synthesis of conformationally constrained adamantane imidazolines with trypanocidal activity

✍ Ioannis Papanastasiou; Andrew Tsotinis; George B. Foscolos; S. Radhika Prathalin 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 373 KB

## Abstract magnified image Aiming at the development of new adamantano building blocks for treating African trypanosomiasis, we report on the synthesis of spiro adamantane 2‐imidazolines **8a‐f** and **9a‐c**, and their congeneric 5‐(1‐adamantyl)imidazolines **14** and **15**. The potency of thes

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ChemInform Abstract: Synthesis of Triazolopyridines as Conformationally Constrained Tertiary Amides.

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