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ChemInform Abstract: Synthesis of Chiral Amino Alcohols Embodying the Bispidine Framework and Their Application as Ligands in Enantioselectively Catalyzed Additions to C=O and C=C Groups.

โœ Scribed by Jan Spieler; Oliver Huttenloch; Herbert Waldmann


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
31
Category
Article
ISSN
0931-7597

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Synthesis of Chiral Amino Alcohols Embod
โœ Jan Spieler; Oliver Huttenloch; Herbert Waldmann ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 358 KB ๐Ÿ‘ 2 views

Two generally applicable routes for the synthesis of chiral amino alcohols embodying the bispidine framework have been developed. In linear route A the bispidine framework is built up successively from chiral primary amines via intermediate formation of a piperidinone and a bispidinone. In convergen