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ChemInform Abstract: Synthesis of Catecholamide Spiroarsoranes and Their in vitro Anthelmintic Properties Against Molinema dessetae and Nippostrongylus brasiliensis Infective Larvae.

✍ Scribed by P. M. LOISEAU; M. TRABELSI; Y. MADAULE; C. BORIES; J.-G. WOLF

Publisher: John Wiley and Sons
Year: 2010
Weight: 30 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199712165

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✦ Synopsis

Synthesis of Catecholamide Spiroarsoranes and Their in vitro

Anthelmintic Properties Against Molinema dessetae and Nippostrongylus brasiliensis Infective Larvae.

-Novel spiroarsoranes, which can be considered as prodrugs of arsonic acids, are synthesized. With respect to the antifilarial activity against Molinema dessetae infective larvae, compounds (IIIc), (VIa), and (VIb) are the most active ones (most yields not given). -(LOISEAU,

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