Two C2-symmetrical bis-epoxides were prepared from/2-mannitol and were subjected to nucleophilic displacements with allylamine and benzylamine. Initial intermolecular epoxide opening, followed by a preferred intramolecular 7-endo-tetragol cyclization, afforded protected polyhydroxyazepanes as major
β¦ LIBER β¦
ChemInform Abstract: Synthesis of C2-Symmetrical Polyhydroxyazepanes as Inhibitors of Glycosidases.
β Scribed by X. QIAN; F. MORIS-VARAS; C.-H. WONG
- Book ID
- 112037454
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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