𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Synthesis of C2-Symmetrical Polyhydroxyazepanes as Inhibitors of Glycosidases.

✍ Scribed by X. QIAN; F. MORIS-VARAS; C.-H. WONG


Book ID
112037454
Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
27
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Synthesis of C2-symmetrical polyhydroxya
✍ Xinhua Qian; Francisco MorΓ­s-Varas; Chi-Huey Wong πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 242 KB

Two C2-symmetrical bis-epoxides were prepared from/2-mannitol and were subjected to nucleophilic displacements with allylamine and benzylamine. Initial intermolecular epoxide opening, followed by a preferred intramolecular 7-endo-tetragol cyclization, afforded protected polyhydroxyazepanes as major

Synthesis of C2-symmetric bis(cyclic iso
✍ Laurence Gauzy; Yves Le Merrer; Jean-Claude Depezay; Dominique Damour-Barbalat; πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 210 KB

Enantiopure C2-symmetric bis(cyclic isothioureas), considered as potent inhibitors of glycosidases, have been synthesized from D-mannitol. The key step involved a mercuriccatalyzed transformation of a cyclic 1,3-thiazolidine-2-thione into a 2-N-tert-butylamino-1,3thiazoline.