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ChemInform Abstract: Synthesis of C2-Functionalized Pyrimidines from 3,4-Dihydropyrimidin-2(1H)-ones by the Mitsunobu Coupling Reaction.

✍ Scribed by Xi-Cun Wang; Guo-Jun Yang; Xiao-Dong Jia; Zhang Zhang; Yu-Xia Da; Zheng-Jun Quan

Publisher: John Wiley and Sons
Year: 2011
Weight: 33 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201135162

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✦ Synopsis

Abstract

The Mitsunobu coupling of 2‐hydroxypyrimidines with N‐, O‐, and acid nucleophiles gives C2‐substituted pyrimidines in high yields.

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