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ChemInform Abstract: Synthesis of Bis(2-arylquinolin-4-yl)amines by Lithium Bis( trimethylsilyl)amide-Mediated Cyclization of Ketimines Derived from 2-( Trifluoromethyl)anilines and Aryl Methyl Ketones.

✍ Scribed by L. STREKOWSKI; L. JANDA; H. LEE


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Synthesis of Bis(2-arylquinolin-4-yl)amines by Lithium Bis( trimethylsilyl)amide-Mediated Cyclization of Ketimines Derived from 2-( Trifluoromethyl)anilines and Aryl Methyl Ketones. -The reaction of ketimines (I) with amide (II) gives the title bis( quinolyl)amines (III) as major products together with silyl derivatives (IV) and trace amounts of two other products. These results are presented as correction of previously published data, which established a product (V) for the above reaction of compound (Ia) . -(STREKOWSKI, L.;