ChemInform Abstract: Synthesis of Benzo(d)-1,2-thiazole-1,1-dioxide Derivatives via Directed Lithiation of 2,2-Dimethyl-N-(phenylsulfonyl)-propanamides.

✍ Scribed by P. STANETTY; B. KRUMPAK; T. EMERSCHITZ; K. MEREITER

• Book ID: 101848921
• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199729118

✦ Synopsis

Synthesis of Benzo(d)-1,2-thiazole-1,1-dioxide Derivatives via Directed Lithiation of 2,2-Dimethyl-N-(phenylsulfonyl)-propanamides.

-A general procedure for the synthesis of benzisothiazoles, whose substitution pattern is not easily accessible by other synthetic methods, is presented. The originally intended formation of 6-membered heterocyclic systems via an aryne-mediated cyclization is not observed. -(STANETTY, P.; KRUMPAK,