ChemInform Abstract: Synthesis and Excha
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C. A. BATTY; M. K. MANTHEY; J. KIRK; M. MANTHEY; R. I. CHRISTOPHERSON; T. HAMBLE
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Article
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2010
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John Wiley and Sons
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Synthesis and Exchange Reactions of 5-Alkyl-2-oxo-6-thioxo-1,2,3,6-Tetrahydropyrimidine-4-carboxylic Acids. -The title compounds are prepared as potential dihydroorotase inhibitors. H/D-exchange studies establish a high tendency towards epimerization at C-5. No epimerization is observed under physi