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ChemInform Abstract: Synthesis of Acylated Methyl β-D-Xylopyranosides and Their Enzymic Deacylations by Rabbit Serum Esterases.

✍ Scribed by V. PETROVIC; S. TOMIC; D. LJEVAKOVIC; J. TOMASIC


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Synthesis of Acylated Methyl β-D-Xylopyranosides and Their Enzymic Deacylations by Rabbit Serum Esterases. -In continuation of earlier works on enzymatic regioselective deacylations of sugars with esterases such as reaction is investigated with different derivatives such as (I), (IV) and (VI). It is noteworthy that no reaction takes place if a pivaloyl group at O-2 is present. The synthesis of the starting materials proceeds via reaction of methyl β-D-xyloypyranoside with different equivalents of pivaloyl chloride in pyridine. Acetylation is achieved using an excess of Ac2O in pyridine. -(PETROVIC,