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ChemInform Abstract: Synthesis of a Tetrasubstituted Bicyclo[2.2.2]octane as a Potential Inhibitor of Influenza Virus Sialidase.

✍ Scribed by Paul W. Smith; Naimisha Trivedi; Peter D. Howes; Steven L. Sollis; George Rahim; Richard C. Bethell; Sean Lynn


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of Substi
✍ Peter Nuhn; A. Herrmann; M. Radman πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 34 KB πŸ‘ 1 views

Synthesis of Substituted Benzoyl Acrylic Acids as Potential Inhibitors of Phospholipase A 2 . -Acylation of long-chain alkylbenzenes with maleic anhydride derivatives under Friedel-Crafts conditions provides access to benzoylacrylic acids [cf. (III)/(IV), (VIII)], which are evaluated for their abili