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ChemInform Abstract: Synthesis of 6-Cyano and 6-Unsubstituted 2-Aryl-8-oxopurine from a Common 2-Oxoimidazole Precursor.

✍ Scribed by Magdi E. A. Zaki; M. Fernanda Proenca

Publisher
John Wiley and Sons
Year
2011
Weight
73 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

Intramolecular cyclization of imines (III) in the presence of DBU results in formation of imidazole derivatives (IV) which are slowly transformed into 6‐cyano oxopurine (V) in the presence of TFA.

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