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ChemInform Abstract: Synthesis of 5(6)-(1-Adamantyl)benzimidazoles.

✍ Scribed by D. S. ZURABISHVILI; M. O. LOMIDZE; SH. A. SAMSONIYA

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Synthesis of 5( 6)-(1-Adamantyl)benzimidazoles.

-The synthesis of some novel 5( 6)-adamantylbenzimidazoles (III) by reaction of the o-phenylenediamine (I) with carboxylic acids or acid chlorides is presented. The benzimidazoles (III) are shown to smoothly undergo N-acylation to afford the 1-N-acyl-5-adamantylbenzimidazoles [β†’ (V)]. N-alkylation requires more rigid reaction conditions. -(ZURABISHVILI, D. S.; LOMIDZE, M. O.;

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