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ChemInform Abstract: Synthesis of 2-Deoxy-3,5-di-O-benzoyl-2,2-difluoro-D-ribose from D-Glucose and D-Mannose. A Formal Synthesis of Gemcitabine.

โœ Scribed by R. FERNANDEZ; M. I. MATHEU; R. ECHARRI; S. CASTILLON


Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Chemoenzymatic Synt
โœ F. YAN; B. V. NGUYEN; C. YORK; T. HUDLICKY ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 1 views

Chemoenzymatic Synthesis of Fluorinated Carbohydrates: 2-Deoxy-2-fluoro-D-glucose and 5-Deoxy-5-fluoro-manno-y-lactol. -The title compounds (III) and (VI) are prepared from the diols (I), which are obtained by microbial oxidation of the corresponding halobenzenes with E. coli JM109. Oxidative cleav