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ChemInform Abstract: Synthesis of 13C-Dehydrocoelenterazine and Model Studies on Symplectoteuthis Squid Bioluminescence.

✍ Scribed by M. ISOBE; M. KUSE; Y. YASUDA; H. TAKAHASHI


Book ID
101875082
Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Synthesis of 13 C-Dehydrocoelenterazine and Model Studies on Symplectoteuthis Squid Bioluminescence.

-Dehydrocoelenterazine is assigned as a chromophoric precursor to its apoprotein. In order to prove this mechanism, the 13 C enriched dehydrocoelenterazine (XIV) is synthesized and reacted with model sulfhydryl compounds such as dithiothreitol (XV) or glutathione. The adducts obtained are fixed under acidic conditions and the structures are discussed.

-(ISOBE, M.; KUSE, M.; YASUDA, Y.;


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