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ChemInform Abstract: Synthesis of 1,1,3,3-Tetraalkylisoindolines Using a Microwave-Assisted Grignard Reaction.

✍ Scribed by Richard C. Foitzik; Steven E. Bottle; Jonathan M. White; Peter J. Scammells

Publisher: John Wiley and Sons
Year: 2008
Weight: 24 KB
Volume: 39
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200833126

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## Abstract The application of microwave technique has been extended successfully for the first time to the synthesis of a representative class of azaphospholes, viz. 1,3‐bis(alkoxycarbonyl)‐1,3‐azaphospholo[5,1‐__a__]isoquinolines (**__2__**), which occurs rapidly giving higher yields. Stereoselec