✦ LIBER ✦
ChemInform Abstract: Synthesis, in vitro anti-HIV Activity, and Biological Stability of 5′-O-Myristoyl Analogue Derivatives of 3′-Fluoro-2′,3′-dideoxythymidine (FLT) as Potential Bifunctional Prodrugs of FLT.
✍ Scribed by K. PARANG; E. E. KNAUS; L. I. WIEBE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Synthesis, in vitro anti-HIV Activity, and Biological Stability of 5'-O-Myristoyl Analogue Derivatives of 3'-Fluoro-2',3'-dideoxythymidine (FLT) as Potential Bifunctional Prodrugs of FLT. -Among several derivatives of the highly active FLT (Ia), the analogues (Ib) and (Ie) are found to be the most effective ones. -(PARANG, K.