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ChemInform Abstract: Synthesis, Antiarrhythmic and Hypotensive Activity of Some Novel 1,3-Disubstituted Ureas and Phenyl N-Substituted Carbamates.

✍ Scribed by Elena G. Chalina; Lidia Chakarova; Dushka T. Staneva

Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199918070

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✦ Synopsis

Synthesis, Antiarrhythmic and Hypotensive Activity of Some Novel 1,3-Disubstituted Ureas and Phenyl N-Substituted Carbamates. -The pharmacological and toxicological investigations of the new compounds indicate that the urea (IIIb) exhibits a strong hypotensive action and the carbamates (Vb) and (Vc) show an antiarrhythmic activity comparable to that of the reference drug propranolol. -(CHALINA, ELENA G.; CHAKAROVA,

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