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ChemInform Abstract: Synthesis and Spectral Properties of Methyl 6-Acetyl- or 6-Cyano-3-amino-2-benzoyl-7-furyl-5-methyl-indolizine-8-carboxylates.

✍ Scribed by M. CHUDIK; S. MARCHALIN; K. HAVRILOVA

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Synthesis and Spectral Properties of Methyl 6-Acetyl-or 6-Cyano-3amino-2-benzoyl-7-furyl-5-methyl-indolizine-8-carboxylates.

-A facile method for the synthesis of the title heterocycles (VI) (6 examples) based on the tandem reaction (Knoevenagel reaction, sigmatropic rearrangement and intramolecular nucleophilic addition) of 2-formyldihydropyridines (IV) with propanenitrile (V) is described.

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