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ChemInform Abstract: Synthesis and Screening of C1-Substituted Tetrahydroisoquinoline Derivatives for Asymmetric Transfer Hydrogenation Reactions.

✍ Scribed by Sai Kumar Chakka; Pher G. Andersson; Glenn E. M. Maguire; Hendrik G. Kruger; Thavendran Govender


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
41
Category
Article
ISSN
0931-7597

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Synthesis of Chiral 1-Substituted Tetrahydroisoquinolines by the Intramolecular 1,3-Chirality Transfer Reaction Catalyzed by Bi(OTf)3. -Treatment of chiral amines of type (I), (III), and (V) with Bi(OTf)3 results in formation of optically active tetrahydroisoquinolines. The (E)/(Z) configuration of